Disparate effects of enkephalin and morphine upon insulin and glucagon secretion by islet cell cultures.
نویسندگان
چکیده
Insulin and glucagon release from monolayer pancreatic islet cell cultures were inhibited in a dose-response fashion by various enkephalins. Morphine, however, stimulated insulin and glucagon release. Both effects were blocked by naloxone, while naloxone alone had no effect. In isolated and denervated islet cells, opiates directly influence secretion from islet cells.
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ورودعنوان ژورنال:
- Diabetes
دوره 29 1 شماره
صفحات -
تاریخ انتشار 1980